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GHRP-2, as a full agonist, drives the receptor above this baseline, but the existence of constitutive activity is part of why the ghrelin/GHS-R1a axis behaves as a rheostat on GH output rather than a simple on/off switch
& Chang, X
Nature (2021) 593(7860):58690
Ameliorative effect of acetylshikonin on ovalbumin OVA-induced allergic rhinitis in mice through the inhibition of Th2 cytokine production and mast cell histamine release
S.Reyero-SaavedraM
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