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This results in the closure of ATP-sensitive potassium (K ATP ) channels, which in turn leads to cell depolarization, the opening of voltage-dependent Ca 2 channels (VDCCs), and the subsequent influx of Ca 2
Broader Medicaid eligibility, gradual tapering of cost-sharing assistance, and increased transparency in drug pricing are proposed policy solutions to reduce these barriers [137], but new legislation is expected to further depress the availability of beneficial drugs, including GLP-1R agonists, reversing attempts to optimize care for those in greatest need [138]
Lakshmanan, B
1 However, many patients stop taking GLP-1s within the first year of treatment due to side effects, cost, insurance barriers, or clinical decisions
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