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Based on studies suggesting people taking a glucagon-like peptide-1 (GLP-1) could be less likely to develop Alzheimers, Novo Nordisk set up two large trials of its drug, semaglutide sold as the popular diabetes and obesity drugs Ozempic and Wegovy
Peak plasma concentrations in humans of dulaglutide were reported as 114 ng/ml (about 2 nM, Geiser et al
GLP-1 agonists carry elevated diabetic ketoacidosis risk in type 1 diabetes and are not standard therapy for this population
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