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Heart (2019) 105(14):107886
Mechanism 3: ROS Scavenging and MITF Suppression UV radiation generates reactive oxygen species that activate the Microphthalmia-associated Transcription Factor (MITF), the primary transcriptional regulator of tyrosinase gene expression
Topical treatment Salicylic acid, BPO, Adapalene, dapsone etc are used as daily treatment
This practice is a precautionary measure to help maintain receptor sensitivity and optimize long-term benefits
Cancer Cell 28 , 569581 (2015)
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