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How To Test Your B12 Level Serum B12 (cobalamin) in the blood is the standard way to check B12 status
Those with conditions like pernicious anemia may need lifelong B12 therapy
Pernicious Anaemia is Lifelong: If your deficiency is due to pernicious anaemia (lack of intrinsic factor), B12 injections will be lifelong, as the underlying absorption problem is permanent