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doi: 10.3390/md17070405 164 TricaB.TriteanN.Constantinescu-AruxandeiD.OanceaF
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This delayed emptying contributes to the satiety effect that helps patients eat less, but it also drives the nausea, vomiting, and constipation reported in the SURPASS-1 trial (N=478), where nausea occurred in 12.8% of patients on tirzepatide 5 mg and 18.6% on 15 mg, versus 6.0% on placebo [4]
There is no single treatment duration that applies to every patient
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