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Gray urges people to consult with a healthcare professional for medical advice if the following occurs: You have not had a period in 3 months or longer You experience heavy bleeding lasting longer than 7 days You have had unpredictable periods for several months You experience severe pain, cramping, dizziness, or fatigue Your period does not regulate after a few months of taking your GLP-1/GIP medication The bottom line Zepbound and other weight loss medications may have an effect on your period

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Seek medical advice if you experience: Persistent palpitations a sensation of your heart racing, pounding, or fluttering that lasts for extended periods or occurs frequently Resting heart rate consistently above 100 beats per minute particularly if this represents a significant change from your baseline Chest pain or discomfort any chest tightness, pressure, or pain, especially if accompanied by shortness of breath Dizziness or lightheadedness particularly if severe or associated with near-fainting episodes Shortness of breath difficulty breathing at rest or with minimal exertion that is new or worsening Unusual fatigue or weakness extreme tiredness that interferes with daily activities Seek emergency medical attention (call 999) if you experience: Severe chest pain or pressure Difficulty breathing or severe shortness of breath Fainting or loss of consciousness Chest pain radiating to the arm, jaw, or back Rapid heart rate accompanied by confusion or altered mental state Patients with pre-existing heart conditions, including arrhythmias, heart failure, or coronary artery disease , should have closer monitoring and may benefit from more frequent follow-up appointments