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While oral supplements can be effective for some, they may not provide the quick boost or high absorption rates needed for people with more significant deficiencies
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PubMed Kruse, T., Sewing, S., Jarl Edsberg, M., Fels, J.J., Hastrup, S., Holst-Hansen, T., Karsdal, M.A., Kramer, S.R., Roth, J., Sidelmann, J.J., Sonne, D.P., Teuteberg, K., Vissing, L., & Henriksen, K
Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team
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