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Nevertheless, the literature reviewed herein points toward the need of more molecular-genetic studies in order to get more insights into synthesis pathways, metal-specificity, and biological and non-biological factors responsible for the induction/expression of, and potential coordination among mechanisms underlying thiol- and non-thiol compounds-assisted metal-chelation

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The bioactivation of amodiaquine by human polymorphonuclear leucocytes in vitro: chemical mechanisms and the effects of fluorine substitution