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et al: Banff 05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy (CAN)
The arginine substitution dramatically reduces IGFBP binding affinity by approximately 1,000-fold relative to native IGF-1 while the N-terminal extension contributes to extended circulating stability
Fatigue during the first one to two weeks is common as the body adjusts to significantly lower caloric intake
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