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The FDA sent over 50 warning letters in September 2025 to companies doing it anyway

Administration Guidelines Proper patient education also includes reviewing storage recommendations, injection technique, site rotation, and recognizing common gastrointestinal side effects that may occur during treatment initiation or dose increases

Decreased appetite affected approximately 1 in 5 treated patients versus less than 1 in 10 taking placebo

Mitochondrial DNA B 6(4):15631565 Marcelline A et al (2020) In vivo antistaphylococcal activity evaluation of Ocimum gratissimum Linn (Lamiaceae) ophthalmic ointment

doi: 10.3390/biom10091211