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Description

In other stem cell classes, such as human or murine-derived adipose-derived stem cells, it has been demonstrated that GLP-1RA upregulates the Wnt signaling pathway and promotes the osteogenic differentiation process and osteogenic gene expression (Lee et al., 2015

Dosages also varied widely in the studies

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The standard protocol in clinical trials started at lower doses (1mg or 2mg weekly) and titrated upward every four weeks to minimize gastrointestinal side effects