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10.1080/15548627.2021.1933299 66 HonischC.RodellaU.GattoC.RuzzaP.TthovJ
The greater change in SF-36v2 physical functioning score between groups was significant in STEPS 1, 2, and 4 (STEP 2, P = .0061
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When intestinal barrier integrity is impaired, gut microorganisms and their structural components can translocate into the systemic circulation and then migrate to lung tissue, where they activate alveolar macrophages and other innate immune cells, thereby initiating or amplifying local inflammatory cascades in the lung (Moon et al., 2025
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