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Following the induction of liver injury by MTX, the TBARS content as an index of lipid peroxidation was significantly increased, indicating the decreased ability of hepatocytes to scavenge free radicals (Figure 2)

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PMID: 8053578 Twersky RS, Goel V, Narayan P, Weedon J (2014) The risk of hypertension after preoperative discontinuation of angiotensin-converting enzyme inhibitors or angiotensin receptor antagonists in ambulatory and same-day admission patients

I recommend scheduling be reviewed ahead of time and patients be given the time they need