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Methods We searched MEDLINE (19962014), EMBase (19742014), and CENTRAL (May 2014) up to June 27, 2014 for randomized controlled trials (RCTs) comparing ALC with placebo or other active medications in diabetic and non-diabetic PNP patients that reported the change of pain using visual analogue scale (VAS)

Ozempic, on the other hand, is only a GLP-1 receptor agonist

Manufacturer rebates are not available if the product is not listed on the formulary

Melanotan-1: Well-tolerated in trials

They are sold as dietary supplements, which means they are not reviewed for safety, effectiveness, or quality the same way prescription GLP-1 treatments are