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While the agreements do not address prices charged to employer health plan sponsors and covered plan members, as drug manufacturers have begun making GLP-1 medications available well below list price through their own direct-to-consumer programs, the major PBMs say they have generally been able to negotiate discounts and rebates for group health plans that effectively bring net costs for these drugs close to DTC costs
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The FDA labeling states that the utility of routine serum calcitonin monitoring or thyroid ultrasound for early detection of MTC in patients treated with tirzepatide is uncertain
Almeida, ALR
Quercetin alleviates cyclophosphamide-induced premature ovarian insufficiency in mice by reducing mitochondrial oxidative stress and pyroptosis in granulosa cells
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