cagrilintide semaglutide combination cagrisema phase 3 results 2024 2025 Novo Nordisk's 2.4 mg / 2.4 mg demonstrated significant reduction in HbA1c and weight across multiple studies in the REIMAGINE program presented at ADA 2026 Cagrilintide–semaglutide (CagriSema) versus semaglutide or
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