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Sobo and Optimal Health Medical
Cells 9:2373
HGH deficiencies are responsible for many of the negative effects of aging that people tend to experience in middle age and beyond, like weight gain, muscle loss, decreased energy levels, poor sleep and low sex drive/sexual dysfunction
Generally speaking, 2 grams per day is considered a safe dosage free from serious side effects
Translational studies using exosomes showed a relationship between the epigenetic modulation of glutamatergic function and a brain metabolic dysfunction known as insulin resistance (IR) as showed by an increase and sex-specific phosphorylation in the expression of IRS1, a key marker of the insulin signaling cascade, in discrete exosomes enriched for the neural cell adhesion molecule L1 (L1CAM), a protein highly expressed in the brain [52, 70,71,72]
