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ROS exert their harmful effects by deactivating enzymes, oxidizing proteins, damaging DNA, initiating lipid peroxidation, and denaturing proteins

These would generally include the use of sunblocks to prevent your skin from exposure to UV rays, avoiding harsh skincare products, and hydration

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

Upon activation, the receptor triggers intracellular signaling cascades, mainly via cyclic adenosine monophosphate (cAMP) production and protein kinase A (PKA) activation