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Semaglutide At a Glance Drug Class: GLP-1 receptor agonist Brand Names: Ozempic (diabetes), Wegovy (weight loss), Rybelsus (oral) Molecular Weight: 4,113 Daltons Half-Life: ~7 days (enables weekly dosing) FDA Approved: 2017 (Ozempic), 2019 (Rybelsus), 2021 (Wegovy) Compounding Status: Illegal since May 2025 (shortage resolved) The Semaglutide Timeline That Changed Everything Semaglutide's journey from diabetes drug to cultural phenomenon reads like a pharmaceutical thriller

[1] Availability varies by state and depends on compounding pharmacy compliance with federal and state law

Little to no weight effect expected

Throughout, we emphasize data and examples from the literature, illustrating each finding with systematic references ( [1] ) ( [2] ) ( [12] ) ( [13] )

Among lowest publicly disclosed pricing