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Abrupt cessation can lead to rebound appetite and other effects that proper tapering can minimize
MTHFR polymorphisms (C677T or A1298C variants) impair methylation enzyme function, leading to elevated homocysteine and reduced SAMe production conditions where methylated B vitamins in Lipo B demonstrably help
Ho HY, Cheng ML, Chiu DT
Diabetes, Obesity & Metabolism, 24 (8), 15531564
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