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Discussion SpaMTP represents an open-source package with an end-to-end analytic pipeline for integrating and analyzing paired SM and ST data

Gomes MB, et al

Q3: Can I take these medicines if I have type 1 diabetes

Published Phase 2 effect sizes most prominently the ~24 percent mean body weight reduction at the 12 mg dose tier in the obesity Phase 2 (PMID 37366315) exceed those reported for dual or single agonists at comparable durations, an outcome that researchers attribute to the additional glucagon-arm contribution to body-composition and energy-expenditure pathways

This dose is then increased over time to 0.5 mg weekly