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The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: Role in cancer pathogenesis and implications for therapeutic approaches
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NANOG plays a crucial role in facilitating the immune evasion of cancer cells by activating the TGF-1 and Tcl1a/Akt signaling pathways, thereby allowing tumor cells to evade immune surveillance and avoid destruction by the immune system [136, 137]
The longest clinical trials extended to 24 weeks (approximately six months) of continuous AOD-9604 administration
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