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In a 16-week study, individuals with obesity and T2D who adhered to a KD regimen experienced an average weight loss of 6.6% and a 16% reduction in HbA1c levels [83].When utilized for the management of T2D, the KD has been associated with weight loss among study participants with minimal side effects [74, 75]
Moreover, the knockdown of tribbles pseudokinase 3 triggers ferroptosis via the SLC7A11/GPX4 pathway, enhancing sunitinib efficacy in clear cell renal cell carcinoma [135]
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