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There are also research findings that it affects mental health

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With reduced preload the heart does not have to exert as much contractile force which reduces the oxygen requirements of the heart and also reduces ventricular transmural pressure resulting in reduced compression of the coronary arteries allowing for more efficient blood flow through the heart

Thus, NRF2 prevents ferroptosis by inducing the expression of genes involved in both GPX4-dependent and GPX4-independent pathways

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