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In contrast, when the concentration of carnitine in the plasma increases and the filtration load of carnitine increases, the kidney rapidly increases the rate of carnitine excretion and reduces its reabsorption efficiency to prevent the excessive accumulation of carnitine in the body

Some interactions with antihypertensive medications have been reported, though clinical significance varies

In this trial, 56 patients with vascular cognitive impairment, who were already taking donepezil (Aricept) were given either 1,500 mg ALC per day or placebo for 28 weeks

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