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For some people, this can also increase stomach pressure, which may cause mild digestive discomfort such as heartburn or indigestion

Start at 250 mcg Before Increasing If you plan to use 500 mcg daily, start at 250 mcg for the first 5-7 days

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Lifestyle weight-loss intervention outcomes in overweight and obese adults with type 2 diabetes: a systematic review and meta-analysis of randomized clinical trials