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Topical creams, transdermal preparations, oral mucosal products are permitted

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Clinical evidence remains limited and outcomes vary by patient

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In addition, a multicenter, randomized controlled trial in patients with T2DM without cardiovascular disease also found that the mean carotid intimal thickness and left carotid intimal thickness after sitagliptin treatment were significantly reduced from baseline, with no significant difference on the right side

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& Grayer, R

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Bhatt DL, Steg PG, Miller M, et al

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