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These metabolic shifts can occasionally activate pain pathways in your brain or reduce pain thresholds temporarily
These pathways are frequently studied in neurobiology research
Participants were randomized to placebo or retatrutide at 1 mg, 4 mg (dose-escalation), 4 mg (no escalation), 8 mg (escalation), 8 mg (no escalation), or 12 mg (escalation) for 48 weeks, following a slow titration protocol
10.1038/jcbfm.2015.45 38 KaurC.LingE
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