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In this study, participants taking orforglipron experienced an average A1C reduction of 2.1% and an average weight loss of 10.1 kilograms at 26 weeks, which was significantly greater than those in the placebo and dulaglutide groups
Nature Structural Biology 10, 19-25
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They reflect real clinical practice where patients know their treatment and can make informed decisions about continuing therapy
These factors can accelerate degradation, making adherence to storage guidelines and expiry dates especially important
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