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Which peptide in KLOW provides the strongest anti-inflammatory effect

GLP-1 receptor agonists like tirzepatide work by slowing stomach emptying and signaling satiety to the brain, but these mechanisms can also influence reproductive hormones and menstrual function

Further, we reasoned that GSH can inhibit PSC activation and proliferation, thereby inhibiting pancreatic fibrosis and protecting islet cells from damage

Read in context, it is a secondary, exploratory outcome from a Phase 2 trial whose primary endpoint, change in cerebral glucose metabolism, was negative, and whose cognitive signal was modest

That said, while the therapeutic potential is massive, the clinical trials for newer peptides are still in early phases