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To prioritize biologically relevant candidates and based on our hypothesis that the evolved protease favors caspase substrates, we cross-referenced the hits with the MerCASBA database 56 of known caspase substrates, identifying potential cleavage events associated with cell death
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In melasma, the Wnt/-catenin pathway is involved in the regulation of fibroblast-secreted factors that modulate melanocytes activity
Peptide digests were acidified to pH 23 with LCMS-grade formic acid (FA
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