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For the full background on Phase 2 trial data which showed average body weight reductions of 24.2% at 48 weeks in the highest-dose cohort researchers should consult the peer-reviewed publication in the New England Journal of Medicine (Jastreboff et al., 2023)
Imaging was performed using the LSM880 Airyscan microscope equipped with a Plan-Apochromat 63/1.40 oil differential interference contrast objective
& Talalay, P
A dosage of 250 g is still very high especially considering that the average content in B12-rich foods is 3-5 g per 100g
For example, more participants taking semaglutide experienced decreased enhanced liver fibrosis scores and decreased liver stiffness than participants on the placebo
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