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Respiratory tissues like nasal membranes lack the high density of GLP-1 receptors found in the alimentary system, so direct drug effects on the nose are biochemically unlikely

At the 24-week mark, participants receiving the drug experienced remarkable reductions in body weight, ranging from -7.2% in the 1 mg group to -17.5% in the 12 mg group, compared to a mere -1.6% in the placebo group