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Bibcode:1993Plant.190..297H

Melasma is frequently associated with: Hormone changes during pregnancy Birth control medications Hormone replacement therapy Genetic predisposition Sun exposure Although melasma is not dangerous, it can be difficult to treat because UV exposure frequently triggers or worsens it

Liraglutide An FDA-approved daily weight loss injection with the longest safety track record

GT-activated prodrugs and potential nephrotoxicity Gamma-glutamyl transferase being the initial and limiting step in GT-activated prodrugs processing and because GT is highly expressed on the luminal surface of the proximal tubules in the kidney, potential nephrotoxicity could have been a limitation in the usage of this class of compound when administered systematically