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In the UK, GLP-1 receptor agonists are primarily prescribed for two main indications : type 2 diabetes mellitus and weight management in adults with obesity or overweight with weight-related comorbidities

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Concerns with treatment cost were also highlighted by T2DXX, as choice of treatment may be made based on affordability for the patient in addition to what is most effective

However, certain symptoms and circumstances warrant medical evaluation to exclude pathological hypercortisolism or other endocrine disorders

It serves as a foundation drug in combination therapy, making it a fundamental component of many diabetes treatment regimens