The process of oxidative stress is a complicated, inter-twined series of events which quite possibly is related to many other cellular processes
95 In one randomized controlled trial involving 144 healthy participants with high non-restorative sleep scores, 120 mg of a standardized extract of ashwagandha root and leaf, called Shoden, daily for six weeks improved time to sleep onset, wakefulness after sleep onset, total sleep time, and sleep efficiency as measured by actigraphy
Therefore, these or other approaches should best be evaluated by future randomized controlled trials, especially in subjects at increased risk of incident T2D and cardiovascular events
DOI: 10.1016/j.freeradbiomed.2009.04.028 29
Clinical Status Human RCT | Observational | Animal | In vitro Primarily studied in preclinical and regional aging research contexts, with limited exploratory human data