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A 2025 clinical study in women with PCOS and obesity (n=56) found tirzepatide led to significant weight reduction (mean 9.54%) and improvement in menstrual regularity: irregular cycles decreased from 85.7% before treatment to 32.1% after

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Clinical studies show that patients receiving lipotropic injections without dietary restriction see minimal weight change the injections optimise fat metabolism pathways that require mobilised fat (from a caloric deficit) to function effectively

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