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The taxonomical features (i.e., phyla and genera) were analyzed via carrying out a linear mixed model [46] on all the features in the data set, whilst taking into account the false discovery rate (type I error) under repeated testing through Benjamini & Hochberg correction [49], of the P-values calculated via type III ANOVA using the Satterthwaites method [47]
Other putative origins investigated in large, population-based datasets include chronic autoimmune syndromes such as inflammatory bowel disease and psoriasis [136, 137], and even after thermal injury, especially in extensive injuries and on sun-exposed body parts [138]
By acting as both a critical shuttle for cellular fuel and a direct precursor to vital neurotransmitters, ALCAR offers a targeted approach to supporting the neurological and metabolic pathways that are so often disrupted in post-viral and neuroimmune conditions
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