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As a triple receptor agonist targeting GLP-1, GIP, and glucagon pathways simultaneously, retatrutide represents one of the most advanced incretinomimetic compounds under investigation for metabolic and obesity research

adverse events should be reported via the Yellow Card scheme at yellowcard.mhra.gov.uk

The optimal approach requires individualised assessment considering disease activity, nutritional status, comorbidities, and patient preferences, delivered through multidisciplinary collaboration between gastroenterology, dietetics, and weight management services

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Cell surface F1Fo ATP synthase: a new paradigm