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Once opened, exposure to air/oxygen increases oxidation risk, and using sterile technique (especially for reconstituted solution) is essential
Avoid blowing your nose for 15-20 minutes after administration
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Most people having B12 injections (intramuscular) will see an improvement in the first 24 hours, but the hematological response, including the quick production of new red blood cells, may take several days to months for a full response
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