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The primary endpoint was HbA 1c after 26 weeks of treatment

It works by mimicking a hormone in the body that helps control blood sugar levels, reduces appetite, and slows down how quickly food leaves the stomach

The dosing schedule typically begins at 2.5 mg weekly for four weeks, with gradual increases every four weeks as tolerated to achieve optimal therapeutic effect

Key benefits included a reduction in phlebotomy requirements, a decrease in spleen size in 75% of patients with splenomegaly, and a significant reduction in pruritus, a common symptom in PV