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& Pendergast, J

Both the SARC021 (in sarcoma patients) and MAESTRO (in pancreatic cancer patients), phase III trials showed that adding evofosfamide to standard chemotherapy (doxorubicin in soft-tissue sarcoma and gemcitabine in pancreatic cancer) failed to improve overall survival compared to chemotherapy alone (283, 284)

Use a separate syringe for each and inject at different sites

4 In asymptomatic patients with low-normal levels of vitamin B 12 (200 to 350 pg per mL [147.56 to 258.23 pmol per L]), elevated levels of the precursor compounds homocysteine and methylmalonic acid may prompt a decision to supplement patients with vitamin B 12

Science 391 , eady5532 (2026)