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For a detailed comparison, see our semaglutide vs tirzepatide comparison page
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In practical terms: Tirzepatide offers well-documented, steady metabolic support and weight-loss results
Extreme caloric restriction while on semaglutide can lead to muscle loss, nutritional deficiencies, and metabolic adaptation that makes long-term weight maintenance harder
Even without the diagnosis of BED, up to 60 percent of people with obesity report experiencing food noise or thinking about food constantly which leads to distress and dysregulated eating behaviors, like loss of control eating and binge eating
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