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Patients with a family history of heart attack, stroke or diabetes, or patients who themselves have been diagnosed with prediabetes, might want to consider being on a small dose of semaglutide to improve metabolic function and possibly for the anti-aging effects, Aziz said
This risk is higher if you have severe kidney problems or drink excessive alcohol
Consequently, GIP and GLP-1 receptor agonists exhibit complementary and potentially synergistic actions, suggesting that their combined administration may further enhance glucose regulation and support weight reduction
The article says patients with established cirrhosis require specialised hepatology evaluation before initiation, because safety data in advanced liver disease remain limited
Renukuntla, J., et al
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