glp-1 leaky gut Tirzepatide, a dual agonist of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), positively impacts the altered microbiota of obese, diabetic, ovariectomized mice How Akkermansia Boosts GLP-1 for

However, this often means taking supraphysiological doses, which may increase the risk of side effects like joint swelling and insulin resistance

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In 2020, South Korean researchers based out of Chungnam National University conducted a systematic review to understand whether coffee enemas have clinical benefits

This is not an argument against GLP-1 drugs

doi: 10.1177/10600280231190089