Despite these positive findings, one caveat is that we do not know the effects of this newer therapy on cardiovascular outcomes but this will be forthcoming in future trials
In April, the agency warned that some compounded semaglutide products contain salts and impurities, unlike the approved formulations, and may be less safe and effective
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8 Moreover, one should consider the fact that different GLP-1 RAs were used across the studies, with different chemical structures, durations of action and weight-lowering effects, which may impact their efficacy