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Lancet Diabetes Endocrinol 4(8):706716
AR and DBZ conceived the study
Compounded PT-141 for women, including post-menopausal women, is off-label but widely used in clinical compounding practice under prescriber care
It works by mimicking a hormone called Glucagon Like Peptide-1 (GLP-1) and exhibits effects such as reducing appetite by acting on centres in the brain as well as acting on the stomach to promote a sense of fullness
This dual effect on both sides of the energy balance equation is why retatrutide produced the highest weight loss percentages of any single-agent trial
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