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Kalagi NA, Thota RN, Stojanovski E, et al

Patients should be reassured that experiencing nausea does not indicate treatment failure or harm, and that symptom improvement is expected with continued use for most people

Before the appointment, patients should document the timing, location, and character of their muscle symptoms, any associated factors (such as relationship to exercise or time of day), and any other new symptoms

These results suggest that the renal and hypertension components promote the progression of fibrosis beyond the cardiac vasculature

As the microbiome becomes less diverse and the gut barrier becomes more permeable over the course of a lifetime, systemic immune activation increases