High-altitude pulmonary hypertension is associated with a free radical-mediated reduction in pulmonary nitric oxide bioavailability
Tajouri, L., V
Instead, it works by supporting tissue repair, reducing inflammation, and promoting healing in areas like muscles, tendons, and ligaments

In the peroxisome proliferator-activated receptor (PPAR)-induced COPD model, upregulation of GPX3 expression can reduce lung tissue damage caused by oxidative stress ( As mentioned earlier, the vast majority of GPX3 is secreted by the renal proximal convoluted tubules, so we speculate that the kidney may be a highly expressed organ of GPX3, and to test our hypothesis, we analyzed the GSE111159 dataset (This dataset mainly detects the gene sequencing of 10 tissues and organs of mouse kidney, liver, brain, lung, thymus, muscle, spleen, stomach, heart and testicle under physiological conditions to understand the gene expression of each tissue and organ) in the GEO database (Gene Expression Omnibus, We found that GPX3 had the highest level of expression in kidney tissue under mouse physiology (Figure 3A), which is consistent with the results of the analysis by Kim et al
In rice, aluminium exposure causes practically all APX isoforms to become active